August 15

Sinemet – Zorro’s Mask

Sinemet – The Mask Of Zorro

Sinemet Mothers Little Helper“Sinemet is an antidyskinetic combination. Levodopa is transformed by the body and the brain into a substance that helps to decrease tremors and other symptoms of Parkinson disease. Carbidopa helps levodopa to reach the brain.” I say; “Gesundheit!”.

I have only been on Sinemet about a week now but, I will share what I know, my experience and was told by my neurologist. I had a horrible reaction on my first dose. I became very ill and had to be picked up from work.
So you ask, “does it work?”. Well the difference is night and day! I was started on two doses a day at a dosage of 25/100 and was instructed to take three or more daily as needed should my symptoms rear their ugly heads. Except before bedtime, there is no need to take Sinemet before turning in for the evening.

As far as any side effects, after the horrible experience with my first dose, I notice no side effects at all. The drug masks my symptoms so well, you wouldn’t even know I had Parkinsonian Syndrome. I can’t even tell I have it except for a slight balance issue which, is pretty much the norm for me anyhow. Mothers little helper Sinemet, is doing the trick. I do however still suffer from frozen shoulder (the medical term is adhesive capsulitis) from time to time but, not nearly as painful as it used to be, just a bit inconvenient.

Should you want to take supplements with medication, it’s best to consult your doctor with a copy of the labels from the stuff you want to take. Even your daily multivitamin can prevent the medication from working properly or interact negatively. Supplements with metals like zinc and iron need to be avoided. This is serious. They may interact and cause very harmful effects. The absorption of levodopa may decrease and cause an increase in your symptoms of Parkinsonism. Before you take your first dose, STOP TAKING ANY VITAMINS OR SUPPLEMENTS! St. Johns Wort; Actually illegal in some countries due to drug interaction. I don’t know about interactions first hand but, I was previously taking St. Johns Wort to help relieve stress along with other supplements.

I mentioned this before but, we put a page here that includes the supplements to treat anxiety and Parkinson’s symptoms that Jim came up with. This could be useful for anyone not using Sinemet or prescription drugs. They sure helped me get through some tough times. I am not taking these supplements currently but, plan to take some in the future as we do more research and share / confirm our findings with the doctor.
Update: I am now back to taking my two soft gels consisting of 400mg of Eicosapentaenoic Acid(EPA), 1000mg of Docosahexaenoic Acid(DHA) and 1500mg Omega-3 Fatty Acids (from purified fish oil) daily 30 minutes before or 60 minutes after my Simenet.

Protein; When food is taken with levodopa (L-dopa), protein in the food can interfere with absorption of this medicine into your bloodstream. Additionally, high blood levels of protein can interfere with transport of this medicine from your blood into your brain, where the medicine actually works. I personally, take my Sinemet a half hour before or an hour after eating. Watch your diet, this is a gimme. You are what you eat, garbage in garbage out and so on. We do not eat fast food at all and processed food once or twice a month because I LOVE pizza. My hubby does do all the cooking from scratch and is very particular about sourcing his ingredients and seasonings. You should consider NEVER EVER EATING ANY FAST FOOD from a health, financial and environmental perspective! As Jim says, “Become part of the solution, not the problem.”.

Below is right from the Michael J. Fox Foundation Website.

No one specific diet is recommended for everyone with Parkinson’s disease. Still, what you eat may impact how well your medication works and can help some of the non-motor symptoms that are associated with PD. For general health and well-being, doctors encourage people with Parkinson’s to follow a balanced diet, which includes whole grains, healthy fats (in foods like nuts, avocado and olive oil) and antioxidants. Antioxidants are molecules that clear out free radicals — substances that are potentially toxic to cells. Free radicals are formed in the body from normal metabolism, but are increased by exposure to environmental toxins, such as cigarette smoke and air pollution. Free radicals contribute to a condition called oxidative stress, which is associated with aging and Parkinson’s disease. A diet high in antioxidants may therefore help to offset oxidative stress, although proof is lacking at this time.

Vegetables: artichokes, okra, kale, bell peppers, potatoes
Fruits: berries, pears, apples, grapes
Legumes: kidney beans, edamame, lentils
Nuts: pecans, walnuts, hazelnuts
Dark chocolate
Red wine (in moderation), coffee, tea I am good with that!

Should I follow a gluten-free diet? No large, randomized-controlled clinical trials have been done on gluten-free diets for PD. Anecdotally, however, many people with Parkinson’s have shared that their symptoms improved when they followed this type of diet. If you personally feel better on a gluten-free diet, there is no medical reason o stop. But before cutting out gluten, weigh the pros and cons. Think about how difficult this type of program may be for you and your family to maintain (shopping, preparing meals, eating out, etc.) and if it might be too socially-restrictive. If the positives outnumber the negatives, you may decide you want
to give it a try for a short period of time. However, strict diets like a gluten-free one can be difficult to maintain.

Okay, back to my ramblings again….
Where to get the best deal on Sinemet?

Well, if you are not able to afford health insurance, welcome to the club. Spending one quarter to one third of our income on health insurance is not an option. Of course we get fined on our taxes at the end of the year because we are “to poor” to afford health insurance but in the “incorrect bracket” to qualify for government assistance! Thanks Obama! In actuality, we would not accept government assistance for anything. The whole “part of the problem vs solution” thing. That however, is another blog and I do believe my husband has that covered. So, speaking of “clubs”, my husband discovered that Sams Club has the lowest cost on ANY meds BUT, you must be premium members. That’s okay, the annual membership fee is covered in the money we save on his and my meds in ONE MONTH. Sinemet for 80 25/100 tabs is under $9.00 there. My husband has to take Carvedilol, Amlodipine and Atorvastatin daily and that is amazingly under 20 a month at Sams club. Without a Sams club Premium membership, we would be well over a hundred bucks a month on meds. Thanks to Sam’s Club and a phone app we use faithfully called Viggle, which gives us a fifty dollar Walmart card card once a month, our meds are basically free, for now. Necessity is the mother of…. innovation?

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